The E2F2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to E2F2. This antibody recognizes Human, and Mouse antigen. The E2F2 Antibody has been validated for the following applications: Western Blot.
Description
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F2 binds specifically to RB1 in a cell-cycle dependent manner.Ivey-Hoyle M., Mol. Cell. Biol. 13:7802-7812(1993).Gregory S.G., Nature 441:315-321(2006).Novy M., Mol. Biol. Cell 16:2181-2190(2005)